Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23624389 | 0.84 | ABL1 (0.49) | NCOA1NCOA3TNFKDRTTBK1 | |
| SCHEMBL29638477 | 0.84 | TNF (0.57) | TNFMAPTMEN1KMT2AEGFR | |
| SCHEMBL29638557 | 0.83 | PIK3CA (0.51) | TNFMEN1KMT2APIP4K2A | |
| SCHEMBL13686770 | 0.82 | MAPK1 (0.56) | TNFMAPTMEN1KMT2ANPC1 | |
| SCHEMBL23611032 | 0.82 | TNF (0.78) | TNFMAPTGRM1EGFRHTT | |
| SCHEMBL30012590 | 0.82 | TNF (0.78) | TNFMAPTGRM1EGFRHTT | |
| SCHEMBL31098947 | 0.81 | RAB9A (0.59) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL29638511 | 0.81 | DYRK1A (0.47) | NCOA1NCOA3MAPTMEN1KMT2A | |
| SCHEMBL29638579 | 0.81 | TRPA1 (0.44) | NCOA1NCOA3TNFMAPTNPC1 | |
| SCHEMBL25117237 | 0.79 | ABL1 (0.49) | TNFMAPTGRM1EGFRTTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |