SCHEMBL29638545 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	RAF1	P04049	2/20	0.43

▸	BRAF	P15056	2/20	0.43

▸	CSF1R	P07333	1/20	0.43

▸	ARAF	P10398	1/20	0.43

▸	DDR1	Q08345	1/20	0.43

▸	DDR2	Q16832	1/20	0.43

▸	EGFR	P00533	13/20	0.36

▸	IDO1	P14902	1/20	0.36

▸	GRM4	Q14833	1/20	0.33

▸	HDAC3	O15379	1/20	0.33

▸	HDAC1	Q13547	1/20	0.33

▸	HDAC6	Q9UBN7	1/20	0.33

▸	EPHA2	P29317	1/20	0.32

▸	KDR	P35968	1/20	0.32

▸	EPHB4	P54760	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29638581	0.93	RAF1 (0.43)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL29638578	0.86	RAF1 (0.43)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL29638706	0.85	RAF1 (0.45)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL29638590	0.84	RAF1 (0.44)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL29638600	0.84	RAF1 (0.44)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL29638629	0.84	RAF1 (0.41)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL29638661	0.81	EGFR (0.45)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL29638490	0.76	MAPK14 (0.31)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL24399558	0.75	RAF1 (0.54)	RAF1BRAFCSF1RARAFDDR1
SCHEMBL30162852	0.75	RAF1 (0.54)	RAF1BRAFCSF1RARAFDDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022089219-A1	ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF	四川科伦博泰生物医药股份有限公司	2022-05-05	—	—	WO	disclosed