Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | ARAF | P10398 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 18/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638578 | 0.90 | RAF1 (0.43) | RAF1CSF1RARAFBRAFDDR1 | |
| SCHEMBL29638706 | 0.89 | RAF1 (0.45) | RAF1CSF1RARAFBRAFDDR1 | |
| SCHEMBL29638581 | 0.85 | RAF1 (0.43) | RAF1CSF1RARAFBRAFDDR1 | |
| SCHEMBL29638661 | 0.84 | EGFR (0.45) | RAF1CSF1RARAFBRAFDDR1 | |
| SCHEMBL29638545 | 0.84 | RAF1 (0.43) | RAF1CSF1RARAFBRAFDDR1 | |
| SCHEMBL29638600 | 0.83 | RAF1 (0.44) | RAF1CSF1RARAFBRAFDDR1 | |
| SCHEMBL29638590 | 0.82 | RAF1 (0.44) | RAF1CSF1RARAFBRAFDDR1 | |
| SCHEMBL29638518 | 0.77 | FGFR1 (0.36) | RAF1BRAF | |
| SCHEMBL29638666 | 0.77 | MAPK1 (0.36) | RAF1CSF1RBRAFDDR1DDR2 | |
| SCHEMBL29638498 | 0.76 | RAF1 (0.42) | RAF1CSF1RARAFBRAFDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |