Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 16/20 | 0.40 |
| ▸ | AKT1 | P31749 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21955797 | 0.73 | PARP1 (0.51) | KDM4E | |
| SCHEMBL13041957 | 0.73 | DYRK1A (0.36) | — | |
| SCHEMBL22558992 | 0.72 | DYRK1A (0.51) | KDM4ESIRT3TDP1 | |
| SCHEMBL31022899 | 0.72 | DYRK1A (0.51) | KDM4ESIRT3TDP1 | |
| SCHEMBL30437026 | 0.69 | MKNK1 (0.50) | RPS6KB1 | |
| SCHEMBL22907450 | 0.69 | DYRK1A (0.33) | TDP1 | |
| SCHEMBL30437103 | 0.69 | FGFR4 (0.50) | KDM4E | |
| SCHEMBL35211521 | 0.69 | MAPK1 (0.35) | RPS6KB1KDM4ESIRT3TDP1 | |
| SCHEMBL22558950 | 0.69 | SIRT3 (0.49) | KDM4ESIRT3TDP1 | |
| SCHEMBL15544783 | 0.68 | PARP1 (0.41) | RPS6KB1AKT1SIRT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |