Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.50 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | MST1R | Q04912 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30436722 | 0.79 | ALK (0.41) | BRD4MAPK1 | |
| SCHEMBL30108229 | 0.79 | IKBKE (0.62) | MKNK1MKNK2IKBKETBK1MET | |
| SCHEMBL18611803 | 0.79 | IKBKE (0.62) | MKNK1MKNK2IKBKETBK1MET | |
| SCHEMBL30436871 | 0.78 | JAK3 (0.51) | CYP11B2MAPK1 | |
| SCHEMBL30436768 | 0.78 | MKNK1 (0.52) | MKNK1MKNK2CYP11B2 | |
| SCHEMBL30437354 | 0.75 | GRIN2B (0.46) | GRM2 | |
| SCHEMBL30436844 | 0.74 | NR4A2 (0.49) | — | |
| SCHEMBL18616235 | 0.73 | PDPK1 (0.48) | MKNK1MKNK2IKBKETBK1MET | |
| SCHEMBL28481416 | 0.73 | PDPK1 (0.51) | MKNK1MKNK2PDPK1KCNH2ATM | |
| SCHEMBL12683550 | 0.72 | JAK3 (0.51) | MKNK1MKNK2BTKLCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102549-B | 5-Aldehyde heterocyclic amide compound and application thereof | 暨南大学 | 2025-02-11 | — | — | CN | claimed |
| CN-116102549-A | 5-aldehyde heterocyclic amide compound and application thereof | 暨南大学 | 2023-05-12 | — | — | CN | claimed |