Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29638837

Cc1nc(C2[C@H]3CNC[C@@H]23)cs1.O=C(O)C(F)(F)F

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 3/20 0.38
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
SLC6A3 Q01959 4/20 0.34
SLC6A2 P23975 3/20 0.34
SLC6A4 P31645 3/20 0.34
CHRNA7 P36544 1/20 0.34
ECE1 P42892 2/20 0.33
MAPK1 P28482 1/20 0.32
NPC1 O15118 1/20 0.32
KDM4A O75164 1/20 0.32
KDM4B O94953 1/20 0.32
KDM5C P41229 1/20 0.32
KDM5B Q9UGL1 1/20 0.32
KCNH2 Q12809 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL20584909 1.00 SSTR4 (0.38) SSTR4RAB9AKDM4EPOLBGAA
Trifluoroacetic Acid SCHEMBL30241438 0.73 KDM5A (0.43) POLBHTTSLC6A3SLC6A2SLC6A4
Trifluoroacetic Acid SCHEMBL25296943 0.73 RAB9A (0.33) RAB9AKDM4EPOLBGAAHTT
SCHEMBL20586011 0.71 RAB9A (0.38) RAB9AKDM4EPOLBGAAHTT
SCHEMBL20587746 0.71 RAB9A (0.38) RAB9AKDM4EPOLBGAAHTT
SCHEMBL20586014 0.71 RAB9A (0.38) RAB9AKDM4EPOLBGAAHTT
SCHEMBL20586012 0.71 RAB9A (0.38) RAB9AKDM4EPOLBGAAHTT
Trifluoroacetic Acid SCHEMBL27323699 0.71 RAB9A (0.38) RAB9AKDM4EPOLBGAAHTT
Trifluoroacetic Acid SCHEMBL30241469 0.71 SSTR4 (0.50) SSTR4
Trifluoroacetic Acid SCHEMBL21063424 0.69 CHRNA7 (0.35) SLC6A3SLC6A2SLC6A4CHRNA7CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3638658-B1 PHARMACEUTICAL COMPOUNDS NXERA PHARMA UK LTD (GB) 2025-10-08 EP disclosed
CN-110944992-B Pharmaceutical compounds 赫普泰雅治疗有限公司 2023-05-16 CN disclosed
US-11352342-B2 Pharmaceutical compounds HEPTARES THERAPEUTICS LIMITED (GB) 2022-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352342-B2 Pharmaceutical compounds CHRM1, CHRM2, CHRM4 SSTR4 391/4885RAB9A 1785/4885KDM4E 3256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.