SCHEMBL29638844

SCHEMBL29638844

Cn1nccc1C1[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H]12

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 1/20 0.39
GPR119 Q8TDV5 5/20 0.39
NR1H2 P55055 1/20 0.39
NAMPT P43490 1/20 0.39
JAK3 P52333 1/20 0.39
RORC P51449 1/20 0.38
USP30 Q70CQ3 1/20 0.38
POLB P06746 1/20 0.38
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21137327 1.00 SSTR4 (0.39) SSTR4GPR119NR1H2NAMPTJAK3
SCHEMBL20585957 0.80 HCAR2 (0.41) KDM4E
SCHEMBL20585956 0.80 HCAR2 (0.41) KDM4E
SCHEMBL20585954 0.80 HCAR2 (0.41) KDM4E
SCHEMBL31141603 0.80 NR1H2 (0.40) SSTR4GPR119NR1H2NAMPTJAK3
SCHEMBL12539635 0.80 PDE4B (0.47) GPR119USP30KDM4E
SCHEMBL29918474 0.79 GPR119 (0.50) GPR119KDM4E
SCHEMBL12539534 0.79 JAK2 (0.48) GPR119USP30KDM4E
SCHEMBL21137324 0.74 MGLL (0.50) SSTR4GPR119NR1H2NAMPTJAK3
SCHEMBL29638842 0.74 MGLL (0.50) SSTR4GPR119NR1H2NAMPTJAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3638658-B1 PHARMACEUTICAL COMPOUNDS NXERA PHARMA UK LTD (GB) 2025-10-08 EP disclosed
CN-110944992-B Pharmaceutical compounds 赫普泰雅治疗有限公司 2023-05-16 CN disclosed
US-11352342-B2 Pharmaceutical compounds HEPTARES THERAPEUTICS LIMITED (GB) 2022-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352342-B2 Pharmaceutical compounds CHRM1, CHRM2, CHRM4 SSTR4 391/4885GPR119 107/4885NR1H2 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.