Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27535192 | 0.85 | CYP1A2 (0.56) | PARP10CYP1A2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL30075020 | 0.82 | SMN1; SMN2 (0.47) | FDPSCYP1A2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL28362308 | 0.81 | CYP1A2 (0.49) | FDPSCYP1A2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL27875620 | 0.80 | CYP1A2 (0.53) | FDPSPARP10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL30867608 | 0.78 | PTPRA (0.43) | FDPSPARP10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL30417793 | 0.78 | ADORA3 (0.40) | CYP1A2SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL30593975 | 0.78 | ADORA3 (0.40) | CYP1A2SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL7449423 | 0.78 | FDPS (0.47) | FDPSCYP1A2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL27585616 | 0.78 | RECQL (0.39) | CYP1A2LMNA | |
| SCHEMBL27691341 | 0.78 | CYP3A4 (0.39) | CYP1A2SMN1; SMN2ALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836301-A | 2, 2-difluoro-5H- [1,3] dioxolo [4,5-F ] isoindol-7-one derivatives as pesticides | 先正达农作物保护股份公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117729920-A | Carboxamide pyrrolopyrazines and pyridine compounds useful as MYT1 inhibitors and their use in the treatment of cancer | 修复治疗公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117377496-A | Compounds for degrading alpha-synuclein aggregates and uses thereof | 新旭生技股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-116981665-A | Novel compounds | 思瑞万斯公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-115916783-A | Compounds, pharmaceutical compositions and methods of making compounds and methods of use thereof | 修复治疗公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115811976-A | Methods of using MYT1 inhibitors | 修复治疗公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-115484933-A | Hot melt extrusion solid dispersions containing BCL2 inhibitors | 广州麓鹏制药有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-109890817-B | 8- (azetidin-1-yl) - [1,2,4] triazolo [1,5-a ] pyridinyl compounds, compositions, and methods of use thereof | 豪夫迈·罗氏有限公司 | 2022-06-17 | — | — | CN | disclosed |