SCHEMBL29639043

SCHEMBL29639043

Cc1ccc2nc(C)cnc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.54
NQO2 P16083 1/20 0.54
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
EGFR P00533 1/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 1/20 0.44
NCK1 P16333 1/20 0.39
BACE1 P56817 1/20 0.39
CCNB2 O95067 1/20 0.39
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CDK5 Q00535 1/20 0.39
CDK5R1 Q15078 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6844954 1.00 CYP1A2 (0.54) CYP1A2NQO2MAPTLMNARAB9A
SCHEMBL29639029 0.91 CYP1A2 (0.54) CYP1A2NQO2MAPTLMNARAB9A
SCHEMBL8344116 0.91 CYP1A2 (0.54) CYP1A2NQO2MAPTLMNARAB9A
SCHEMBL30578800 0.91 CYP1A2 (0.54) CYP1A2NQO2MAPTLMNARAB9A
SCHEMBL15037485 0.84 PDGFRB (0.45) CYP1A2NQO2MAPTLMNARAB9A
Ethoxycarbonyl Group SCHEMBL28040931 0.81 TDP1 (0.39) CYP1A2NQO2MAPTLMNARAB9A
SCHEMBL101566 0.79 KMT2A (0.48) KDM4EBACE1CCNB2CDK1CCNB1
SCHEMBL1641255 0.79 PABPC1 (0.44) CYP1A2NQO2MAPTSMN1; SMN2MAPK1
SCHEMBL19001484 0.79 NQO2 (0.50) CYP1A2NQO2MAPTLMNARAB9A
SCHEMBL2629410 0.79 ALDH1A1 (0.46) MAPTLMNAALDH1A1KDM4ECCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410146-A One-step process for converting polyols to nitrogen-containing heterocycles using heterogeneous metal catalysts 浙江大学 2023-07-11 CN disclosed
CN-113087674-B Method for synthesizing quinoxaline compound under catalysis of visible light induced photosensitizer 河南大学 2022-06-17 CN disclosed