SCHEMBL29639044

SCHEMBL29639044

Cc1cnc2cc(Cl)c(Cl)cc2n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
HRH4 Q9H3N8 1/20 0.41
SORD Q00796 1/20 0.39
LMNA P02545 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MAPT P10636 1/20 0.37
GLP1R P43220 3/20 0.36
PDGFRB P09619 2/20 0.36
NPC1 O15118 1/20 0.36
KDR P35968 1/20 0.36
FLT3 P36888 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CDK1 P06493 2/20 0.36
CCNB2 O95067 1/20 0.36
CCNB1 P14635 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15508247 1.00 ALDH1A1 (0.52) ALDH1A1HRH4SORDLMNAMMP1
SCHEMBL21225653 0.86 ALDH1A1 (0.44) ALDH1A1HRH4SORDLMNAMAPT
SCHEMBL21225611 0.86 ALDH1A1 (0.44) ALDH1A1HRH4SORDLMNAMAPT
SCHEMBL24140225 0.85 ALDH1A1 (0.48) ALDH1A1MAPTPDGFRBNPC1KDR
SCHEMBL2679771 0.81 ALDH1A1 (0.61) ALDH1A1MAPTPDGFRBNPC1KDR
SCHEMBL29639032 0.81 ALDH1A1 (0.61) ALDH1A1MAPTPDGFRBNPC1KDR
Phenylhydrazine SCHEMBL28910538 0.80 PDGFRB (0.46) ALDH1A1LMNAMAPTPDGFRBNPC1
SCHEMBL21591903 0.79 PGK1 (0.55) ALDH1A1LMNAMAPTGLP1RPOLB
SCHEMBL21591867 0.79 PGK1 (0.55) ALDH1A1LMNAMAPTGLP1RPOLB
SCHEMBL28603223 0.77 ALDH1A1 (0.42) ALDH1A1PDGFRBNPC1KDRFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118480071-A Novel chiral PNN ligand, manganese complex thereof, preparation method and application 中国科学院上海有机化学研究所 2024-08-13 CN disclosed
CN-116410146-A One-step process for converting polyols to nitrogen-containing heterocycles using heterogeneous metal catalysts 浙江大学 2023-07-11 CN disclosed
CN-113087674-B Method for synthesizing quinoxaline compound under catalysis of visible light induced photosensitizer 河南大学 2022-06-17 CN disclosed