SCHEMBL29639045

SCHEMBL29639045

Brc1cc2nccnc2cc1Br

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
CHRNB4 P30926 2/20 0.34
CHRNA3 P32297 2/20 0.34
CHRNA1 P02708 1/20 0.34
ESR1 P03372 1/20 0.34
CHRNG P07510 1/20 0.34
CHRNB1 P11230 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNA5 P30532 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
HTR3A P46098 1/20 0.34
CHRND Q07001 1/20 0.34
CHRNA2 Q15822 1/20 0.34
CCNB2 O95067 1/20 0.34
CDK1 P06493 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18388861 1.00 HTT (0.36) HTTCYP1A2CYP2C19NPC1RAB9A
SCHEMBL11770393 0.81 ALOX15 (0.37) HTTCYP1A2CYP2C19NPC1RAB9A
SCHEMBL3302189 0.81 ALDH1A1 (0.35) HTTCYP1A2CYP2C19NPC1RAB9A
SCHEMBL3307757 0.81 AHR (0.41) HTTCYP1A2CYP2C19NPC1RAB9A
SCHEMBL3304131 0.81 ALDH1A1 (0.40) HTTCYP1A2CYP2C19NPC1RAB9A
SCHEMBL1612114 0.78 CHRNB4 (0.40) NPC1RAB9ACHRNB4CHRNA3CHRNA1
SCHEMBL22324000 0.75 PDGFRB (0.46) CCNB2CDK1CCNB1GSK3AGSK3B
SCHEMBL3307262 0.75 MAPK1 (0.33) ALDH1A1MAPK1HSD17B10ALOX15MAPK10
SCHEMBL30217734 0.75 MAPK1 (0.33) CCNB2CDK1CCNB1GSK3AGSK3B
SCHEMBL16040498 0.75 MAPK1 (0.33) CCNB2CDK1CCNB1GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028592-A Photochromic diaryl ethylene compound and preparation method and application thereof 济宁医学院 2022-09-09 CN claimed
CN-117777031-A Synthesis method of 2-phenyl quinoxaline derivative under photocatalysis condition 福建医科大学 2024-03-29 CN disclosed
CN-115028592-A Photochromic diaryl ethylene compound and preparation method and application thereof 济宁医学院 2022-09-09 CN disclosed
CN-113087674-B Method for synthesizing quinoxaline compound under catalysis of visible light induced photosensitizer 河南大学 2022-06-17 CN disclosed