Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741248 | 1.00 | GAA (0.56) | GAANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL29639182 | 0.84 | GAA (0.65) | GAANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL7296019 | 0.82 | MAPT (0.64) | GAANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL28741251 | 0.79 | GAA (0.58) | GAANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL28741203 | 0.78 | GAA (0.58) | GAANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL29639141 | 0.78 | GAA (0.58) | GAANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL23121252 | 0.77 | GAA (0.62) | GAANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL22192215 | 0.77 | NPC1 (0.86) | NPC1MAPTSMN1; SMN2RAB9APOLB | |
| SCHEMBL28741191 | 0.76 | MEN1 (0.54) | GAANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL29639148 | 0.76 | MEN1 (0.54) | GAANPC1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436978-B | Antifungal compound and application thereof | 中国人民解放军海军军医大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-114436978-A | Antifungal compound and application | 中国人民解放军海军军医大学 | 2022-05-06 | — | — | CN | disclosed |