Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302094 | 0.85 | SMN1; SMN2 (0.76) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL7295349 | 0.85 | MAPT (0.72) | MAPTSMN1; SMN2KCNK9NPC1RAB9A | |
| SCHEMBL7291413 | 0.85 | SMN1; SMN2 (0.76) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL29639182 | 0.85 | GAA (0.65) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL29639154 | 0.82 | GAA (0.56) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL28741248 | 0.82 | GAA (0.56) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL4254168 | 0.81 | TP53 (0.80) | MAPTSMN1; SMN2KCNK9NPC1RAB9A | |
| SCHEMBL7301498 | 0.80 | NR1H4 (0.56) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL21652225 | 0.80 | KCNK9 (0.68) | MAPTSMN1; SMN2KCNK9NPC1RAB9A | |
| SCHEMBL28741251 | 0.80 | GAA (0.58) | MAPTSMN1; SMN2GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |