Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.53 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741251 | 0.94 | GAA (0.58) | GAATHRBRXFP1MAPK1KMT2A | |
| SCHEMBL29639141 | 0.85 | GAA (0.58) | GAATHRBMAPK1KMT2AMEN1 | |
| SCHEMBL28741203 | 0.85 | GAA (0.58) | GAATHRBMAPK1KMT2AMEN1 | |
| SCHEMBL7296019 | 0.85 | MAPT (0.64) | GAATHRBMAPK1KMT2AMEN1 | |
| SCHEMBL16692682 | 0.84 | NPC1 (0.55) | GAAMAPK1KMT2AMEN1MAPT | |
| SCHEMBL18027782 | 0.84 | SMN1; SMN2 (0.66) | GAAMAPK1KMT2AMEN1MAPT | |
| SCHEMBL23121252 | 0.84 | GAA (0.62) | GAAMAPK1KMT2AMEN1MAPT | |
| SCHEMBL28741248 | 0.84 | GAA (0.56) | GAAMAPK1KMT2AMEN1MAPT | |
| SCHEMBL29639154 | 0.84 | GAA (0.56) | GAAMAPK1KMT2AMEN1MAPT | |
| SCHEMBL28741191 | 0.84 | MEN1 (0.54) | GAATHRBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436978-A | Antifungal compound and application | 中国人民解放军海军军医大学 | 2022-05-06 | — | — | CN | disclosed |