Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MAP2 | P11137 | 1/20 | 0.46 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639197 | 0.84 | SERPINE1 (0.53) | PTGS2SERPINE1HPGDKDM4EALDH1A1 | |
| SCHEMBL31047692 | 0.83 | SERPINE1 (0.51) | PTGS2SERPINE1PARP1LMNAHPGD | |
| SCHEMBL29031864 | 0.83 | SERPINE1 (0.51) | PTGS2SERPINE1PARP1HPGDKDM4E | |
| SCHEMBL29639170 | 0.82 | SERPINE1 (0.71) | PTGS2SERPINE1PARP1ESR1ESR2 | |
| SCHEMBL29031884 | 0.82 | SERPINE1 (0.71) | PTGS2SERPINE1PARP1ESR1ESR2 | |
| SCHEMBL29031883 | 0.81 | SERPINE1 (0.67) | PTGS2SERPINE1PARP1LMNAHPGD | |
| SCHEMBL29639174 | 0.81 | SERPINE1 (0.67) | PTGS2SERPINE1PARP1LMNAHPGD | |
| SCHEMBL29639258 | 0.81 | PTGS2 (0.54) | PTGS2SERPINE1LMNAHPGDKDM4E | |
| SCHEMBL29031861 | 0.81 | CSF1R (0.54) | PTGS2SERPINE1PARP1LMNAHPGD | |
| SCHEMBL29639233 | 0.81 | PTGS2 (0.53) | PTGS2SERPINE1KDM4EALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-113666925-B | Method for synthesizing isoindolo [2,1-b ] isoquinoline-5 (7H) -ketone compound | 广州大学 | 2022-05-17 | — | — | CN | disclosed |