Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639616 | 0.98 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 | |
| SCHEMBL29639618 | 0.86 | POLB (0.59) | TRPA1KDM4EPOLBPOLA1PPARG | |
| SCHEMBL2135456 | 0.83 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 | |
| SCHEMBL18730282 | 0.83 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 | |
| SCHEMBL2538214 | 0.83 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 | |
| SCHEMBL430424 | 0.83 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 | |
| SCHEMBL16040409 | 0.83 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 | |
| SCHEMBL430423 | 0.83 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 | |
| SCHEMBL16040410 | 0.83 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 | |
| SCHEMBL2540152 | 0.83 | TRPA1 (0.63) | TRPA1KDM4EPOLBPOLA1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202052-A1 | AROMATIC ALKAMIDES AND METHODS OF USE THEREOF IN TASTE MODULATION | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-06-30 | — | — | US | disclosed |