Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16040409 | 1.00 | TRPA1 (0.63) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL28149740 | 1.00 | TRPA1 (0.63) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL2538214 | 1.00 | TRPA1 (0.63) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL18730282 | 1.00 | TRPA1 (0.63) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL887711 | 1.00 | TRPA1 (0.63) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL18730280 | 1.00 | TRPA1 (0.63) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL16040410 | 1.00 | TRPA1 (0.63) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL2540152 | 1.00 | TRPA1 (0.63) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL370066 | 0.98 | TRPA1 (0.66) | TRPA1KDM4EPPARGPPARAALOX12 | |
| SCHEMBL370068 | 0.98 | TRPA1 (0.66) | TRPA1KDM4EPPARGPPARAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4468884-A1 | LYMPH-RELEASING COMPOSITIONS OF FATTY ACIDS AND USES THEREOF FOR LYMPHATIC INCORPORATION AND SYSTEMIC DISEASE TREATMENT | Amarin Pharmaceuticals Ireland Limited (IE) | 2024-12-04 | — | — | EP | claimed |
| CN-118714935-A | Lymphoreleased fatty acid compositions and their use for lymphatic incorporation and systemic disease treatment | 阿马里纳药物爱尔兰有限公司 | 2024-09-27 | — | — | CN | claimed |
| US-20240173285-A1 | COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-05-30 | — | — | US | claimed |
| EP-4329742-A1 | COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT | Amarin Pharmaceuticals Ireland Limited (IE) | 2024-03-06 | — | — | EP | claimed |
| WO-2023146984-A1 | LYMPH-RELEASING COMPOSITIONS OF FATTY ACIDS AND USES THEREOF FOR LYMPHATIC INCORPORATION AND SYSTEMIC DISEASE TREATMENT | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2023-08-03 | — | — | WO | claimed |
| WO-2022232633-A1 | COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2022-11-03 | — | — | WO | claimed |
| US-9308189-B2 | Nitro fatty acids—neuroprotection and/or inhibition of cognitive decline | NITROMEGA CORP. (US) | 2016-04-12 | — | — | US | claimed |
| US-20140271844-A1 | COMPOSITIONS CONTAINING NITRO FATTY ACIDS | COMPLEXA, INC. | 2014-09-18 | — | — | US | claimed |
| EP-2726086-A2 | COMPOSITIONS CONTAINING NITRO FATTY ACIDS | Nitromega Corp. (US) | 2014-05-07 | — | — | EP | claimed |
| US-20140017219-A1 | NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE | NITROMEGA CORP. (US) | 2014-01-16 | — | — | US | claimed |
| US-8563609-B2 | Nitro fatty acids - neuroprotection and/or inhibition of cognitive decline | NITROMEGA CORP. (US) | 2013-10-22 | — | — | US | claimed |
| WO-2013003689-A2 | COMPOSITIONS CONTAINING NITRO FATTY ACIDS | NITROMEGA CORP. (US) | 2013-01-03 | — | — | WO | claimed |
| US-20110280852-A1 | NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE | NITROMEGA CORP. (US) | 2011-11-17 | — | — | US | claimed |
| EP-2384114-A1 | NUTRACEUTICALS CONTAINING NITRO FATTY ACIDS | Nitromega Corp. (US) | 2011-11-09 | — | — | EP | claimed |
| US-20110256247-A1 | TOPICAL COMPOSITIONS CONTAINING NITRO FATTY ACIDS | NITROMEGA CORP. (US) | 2011-10-20 | — | — | US | claimed |
| WO-2010078504-A1 | NUTRACEUTICALS CONTAINING NITRO FATTY ACIDS | NITROMEGA CORP. (US) | 2010-07-08 | — | — | WO | claimed |
| US-20100166918-A1 | NUTRACEUTICALS CONTAINING NITRO FATTY ACIDS | COMPLEXA, INC. | 2010-07-01 | — | — | US | claimed |
| JP-6212186-A | — | — | None | — | — | JP | disclosed |
| US-20100166918-A1 | NUTRACEUTICALS CONTAINING NITRO FATTY ACIDS | COMPLEXA, INC. | 2010-07-01 | — | — | US | disclosed |
| JP-H06212186-A | PRODUCTION OF EICOSAPENTAENOIC ACID FROM RED ALGA FUDARAKU | AGENCY OF IND SCIENCE & TECHNOL | 1994-08-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140271844-A1 | COMPOSITIONS CONTAINING NITRO FATTY ACIDS | ALOX5, FASN, ALOX12 | TRPA1 639/4885KDM4E 4550/4885PPARG 26/4885 |
| US-20110256247-A1 | TOPICAL COMPOSITIONS CONTAINING NITRO FATTY ACIDS | ALOX5, FASN, FPR1 | TRPA1 276/4885KDM4E 4447/4885PPARG 25/4885 |
| US-20140017219-A1 | NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE | NLN, SMN1; SMN2, ELOVL1 | TRPA1 1861/4885KDM4E 4231/4885PPARG 51/4885 |
| US-20110280852-A1 | NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE | NLN, SMN1; SMN2, CASP10 | TRPA1 1933/4885KDM4E 4215/4885PPARG 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.