Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.74 |
| ▸ | MEN1 | O00255 | 13/20 | 0.74 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | RECQL | P46063 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384563 | 0.85 | KMT2A (1.00) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL29721572 | 0.82 | KMT2A (0.68) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL7747008 | 0.75 | KMT2A (0.68) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL9678054 | 0.72 | KMT2A (0.54) | KMT2AMEN1ELANEF2PLG | |
| SCHEMBL12930176 | 0.72 | ALDH1A1 (0.70) | MAPTALDH1A1ELANEF2PLG | |
| SCHEMBL9678058 | 0.72 | KMT2A (0.54) | KMT2AMEN1ELANEF2PLG | |
| SCHEMBL14870544 | 0.71 | ALDH1A1 (0.62) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL10588160 | 0.70 | KMT2A (0.60) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL10588156 | 0.70 | KMT2A (0.60) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL12237107 | 0.70 | PIM1 (0.83) | KMT2AMEN1MAPTALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516858-A | DprE1 enzyme inhibitor and application thereof | 沈阳药科大学 | 2022-05-20 | — | — | CN | disclosed |