Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | ELANE | P08246 | 4/20 | 0.55 |
| ▸ | CTSG | P08311 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | CTRC | Q99895 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 7/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746377 | 0.84 | KMT2A (0.56) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL5384563 | 0.81 | KMT2A (1.00) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL29639732 | 0.75 | KMT2A (0.74) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL9631717 | 0.75 | PIM1 (0.60) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL12237107 | 0.73 | PIM1 (0.83) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL12237110 | 0.73 | PIM1 (0.83) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL8133525 | 0.72 | ELANE (0.61) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL7833789 | 0.71 | ELANE (0.71) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL11453870 | 0.70 | ELANE (0.70) | KMT2AMEN1ELANECTSGF2 | |
| SCHEMBL10341790 | 0.70 | KMT2A (0.68) | KMT2AMEN1MAPTALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |