Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 4/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28826290 | 0.85 | DEGS1 (0.48) | DEGS1CES2CES1HTTPARP10 | |
| SCHEMBL2678109 | 0.85 | DEGS1 (0.48) | DEGS1CES2CES1HTTPARP10 | |
| SCHEMBL24536035 | 0.79 | DEGS1 (0.49) | DEGS1CES2CES1HTTHDAC6 | |
| SCHEMBL14342568 | 0.79 | DEGS1 (0.49) | DEGS1 | |
| SCHEMBL11920604 | 0.79 | DEGS1 (0.49) | DEGS1 | |
| SCHEMBL15964829 | 0.75 | CA1 (0.50) | DEGS1HTT | |
| SCHEMBL15355925 | 0.71 | DEGS1 (0.52) | DEGS1MLYCDHDAC1HDAC8HDAC6 | |
| SCHEMBL15964826 | 0.71 | CA1 (0.54) | HTT | |
| SCHEMBL5899483 | 0.71 | CES2 (0.75) | CES2CES1 | |
| SCHEMBL2678110 | 0.70 | MEN1 (0.38) | DEGS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | disclosed |