SCHEMBL29639986

SCHEMBL29639986

C1=Cc2ccc3nc4ccccc4cc3c2CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 5/20 0.42
GLA P06280 3/20 0.42
HPGD P15428 3/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 3/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
PTBP1 P26599 1/20 0.42
RCE1 Q9Y256 1/20 0.42
MAPT P10636 2/20 0.41
ACHE P22303 2/20 0.41
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
HTR3A P46098 1/20 0.33
MEN1 O00255 1/20 0.33
IDO1 P14902 1/20 0.33
NQO2 P16083 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22588397 1.00 ALDH1A1 (0.42) ALDH1A1KDM4EGLAHPGDKMT2A
SCHEMBL9561652 0.79 ALDH1A1 (0.41) ALDH1A1KDM4EGLAHPGDKMT2A
SCHEMBL29801033 0.78 ALDH1A1 (0.36) ALDH1A1KDM4EGAAMAPTACHE
SCHEMBL3418047 0.78 ALDH1A1 (0.36) ALDH1A1KDM4EGAAMAPTACHE
SCHEMBL31412074 0.76 MAPT (0.38) ALDH1A1KDM4EKMT2AGAARAB9A
SCHEMBL19810029 0.76 ALDH1A1 (0.35) ALDH1A1KDM4EGAAACHEMAOA
SCHEMBL22591219 0.75 ALDH1A1 (0.38) ALDH1A1KDM4EGLAHPGDKMT2A
SCHEMBL1893653 0.75 HSD17B10 (0.41) ALDH1A1KDM4EGLAHPGDLMNA
SCHEMBL28593235 0.75 KMT2A (0.41) ALDH1A1KDM4EGLAHPGDKMT2A
SCHEMBL29827655 0.72 KMT2A (0.40) ALDH1A1KDM4EGLAHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022139525-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND 주식회사 엘지화학 2022-06-30 WO disclosed
WO-2022139513-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-06-30 WO disclosed