SCHEMBL9561652

SCHEMBL9561652

C1=Cc2ccc3cc4ccccc4nc3c2CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
GLA P06280 1/20 0.41
ACHE P22303 1/20 0.41
HTR3A P46098 1/20 0.37
TERT O14746 1/20 0.32
KDM4E B2RXH2 3/20 0.31
GAA P10253 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
POLB P06746 1/20 0.31
NR4A1 P22736 1/20 0.31
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
PKM P14618 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31412074 0.80 MAPT (0.38) ALDH1A1MAPTKDM4EGAAKMT2A
SCHEMBL22588397 0.79 ALDH1A1 (0.42) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL29639986 0.79 ALDH1A1 (0.42) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL29801033 0.74 ALDH1A1 (0.36) ALDH1A1MAPTACHEKDM4EGAA
SCHEMBL3418047 0.74 ALDH1A1 (0.36) ALDH1A1MAPTACHEKDM4EGAA
SCHEMBL11946888 0.74 LMNA (0.50) ALDH1A1MAPTKDM4ETP53CYP3A4
SCHEMBL19810029 0.73 ALDH1A1 (0.35) ALDH1A1ACHEKDM4EGAACYP3A4
SCHEMBL6492561 0.72 CYP1A2 (0.47) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL31030237 0.72 ALDH1A1 (0.43) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL9099825 0.72 ALDH1A1 (0.43) ALDH1A1MAPTHPGDGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929687-A Acridine compound, and organic semiconductor layer, organic electronic device and display device comprising same 诺瓦尔德股份有限公司 2022-08-19 CN claimed
WO-2021116225-A1 ACRIDINE COMPOUND AND ORGANIC SEMICONDUCTING LAYER, ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING THE SAME NOVALED GMBH (DE) 2021-06-17 WO claimed
EP-3835295-A1 ACRIDINE COMPOUND AND ORGANIC SEMICONDUCTING LAYER, ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING THE SAME Novaled GmbH (DE) 2021-06-16 EP claimed
CN-114929687-A Acridine compound, and organic semiconductor layer, organic electronic device and display device comprising same 诺瓦尔德股份有限公司 2022-08-19 CN disclosed
WO-2021116225-A1 ACRIDINE COMPOUND AND ORGANIC SEMICONDUCTING LAYER, ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING THE SAME NOVALED GMBH (DE) 2021-06-17 WO disclosed
EP-3835295-A1 ACRIDINE COMPOUND AND ORGANIC SEMICONDUCTING LAYER, ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING THE SAME Novaled GmbH (DE) 2021-06-16 EP disclosed
EP-0538392-A1 3-PHENYL-5,6-DIHYDROBENZ C]ACRIDINE-7-CARBOXYLIC ACIDS AND RELATED COMPOUNDS AS IMMUNOSUPPRESIVE AGENTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-04-28 EP disclosed
WO-1992000739-A1 3-PHENYL-5,6-DIHYDROBENZ[C]ACRIDINE-7-CARBOXYLIC ACIDS AND RELATED COMPOUNDS AS IMMUNOSUPPRESIVE AGENTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1992-01-23 WO disclosed