Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | NEK4 | P51957 | 1/20 | 0.40 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14299250 | 0.82 | CHEK1 (0.47) | TAOK1CLK4IDH1PDE10ATP53 | |
| SCHEMBL29626895 | 0.82 | CHEK1 (0.47) | TAOK1CLK4IDH1PDE10ATP53 | |
| SCHEMBL29510641 | 0.81 | ROCK2 (0.39) | ROCK2ROCK1EEF2KMAP4K4CLK2 | |
| SCHEMBL21964510 | 0.81 | ROCK2 (0.39) | ROCK2ROCK1EEF2KMAP4K4CLK2 | |
| SCHEMBL31609633 | 0.81 | ELANE (0.41) | ROCK2ROCK1EEF2KMAP4K4CLK2 | |
| SCHEMBL24552717 | 0.81 | ELANE (0.41) | ROCK2ROCK1EEF2KMAP4K4CLK2 | |
| SCHEMBL29626763 | 0.80 | TP53 (0.36) | TAOK1CLK4ELANEHDAC4TP53 | |
| SCHEMBL29627963 | 0.78 | GABRG2 (0.39) | ROCK2ROCK1EEF2KMAP4K4CLK2 | |
| SCHEMBL21961591 | 0.77 | ROCK2 (0.41) | ROCK2ROCK1EEF2KMAP4K4CLK2 | |
| SCHEMBL30991776 | 0.77 | ROCK2 (0.39) | ROCK2ROCK1EEF2KMAP4K4CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |