Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | GAA | P10253 | 7/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24660945 | 1.00 | ALDH1A1 (0.54) | ALDH1A1GAARXFP1MAPTTDP1 | |
| SCHEMBL21200939 | 0.87 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTTDP1NPSR1 | |
| SCHEMBL31091996 | 0.82 | RXFP1 (0.52) | ALDH1A1GAARXFP1MAPTNPSR1 | |
| SCHEMBL29626593 | 0.82 | RXFP1 (0.52) | ALDH1A1GAARXFP1MAPTNPSR1 | |
| SCHEMBL29866764 | 0.78 | HCRTR1 (0.42) | ALDH1A1GAARXFP1MAPTTDP1 | |
| SCHEMBL28741733 | 0.77 | GAA (0.42) | ALDH1A1GAAMAPTTDP1SMN1; SMN2 | |
| SCHEMBL21199933 | 0.76 | RXFP1 (0.50) | ALDH1A1GAARXFP1MAPTNPSR1 | |
| SCHEMBL29640118 | 0.76 | RXFP1 (0.50) | ALDH1A1GAARXFP1MAPTNPSR1 | |
| SCHEMBL30042580 | 0.75 | RXFP1 (0.73) | ALDH1A1GAARXFP1MAPTTDP1 | |
| SCHEMBL1013325 | 0.75 | RXFP1 (0.73) | ALDH1A1GAARXFP1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |