Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30875892 | 0.88 | NAMPT (0.40) | KDM4EKMT2ACYP1A2NAMPTHRH3 | |
| SCHEMBL29711975 | 0.88 | NAMPT (0.34) | KDM4EKMT2ANAMPT | |
| SCHEMBL16440060 | 0.84 | — | — | |
| SCHEMBL15758654 | 0.81 | CYP1A2 (0.33) | KDM4EKMT2ACYP1A2PARP1NAMPT | |
| SCHEMBL20791651 | 0.80 | LTA4H (0.32) | — | |
| SCHEMBL18828724 | 0.77 | NAMPT (0.43) | KDM4EKMT2ANAMPT | |
| Hydrochloric Acid SCHEMBL3662738 | 0.75 | KDM4E (0.35) | KDM4EKMT2A | |
| SCHEMBL30184062 | 0.75 | CYP1A2 (0.39) | KDM4EKMT2ACYP1A2PARP1NAMPT | |
| SCHEMBL31622199 | 0.74 | KDM4E (0.30) | KDM4E | |
| SCHEMBL31276193 | 0.73 | SOS1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |