Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579540 | 0.91 | AAK1 (0.40) | OPRK1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL28407518 | 0.91 | AAK1 (0.40) | OPRK1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL21112426 | 0.88 | PPARA (0.41) | OPRK1MEN1KMT2ALMNAMAPT | |
| SCHEMBL21112423 | 0.88 | PPARA (0.41) | OPRK1MEN1KMT2ALMNAMAPT | |
| SCHEMBL28407522 | 0.87 | CTSS (0.34) | OPRK1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20908059 | 0.87 | CTSS (0.34) | OPRK1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28407464 | 0.85 | TRPV1 (0.38) | OPRK1SMN1; SMN2CTSSAAK1 | |
| SCHEMBL29640239 | 0.85 | TRPV1 (0.38) | OPRK1SMN1; SMN2CTSSAAK1 | |
| SCHEMBL20907784 | 0.84 | KMT2A (0.39) | OPRK1MEN1KMT2ASMN1; SMN2CTSK | |
| SCHEMBL28403743 | 0.84 | KMT2A (0.39) | OPRK1MEN1KMT2ASMN1; SMN2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352329-B2 | HIV protease inhibitors | GILEAD SCIENCES, INC. (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352329-B2 | HIV protease inhibitors | PRSS1, SERPINB1, FURIN | OPRK1 2622/4885MEN1 2814/4885KMT2A 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.