Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.69 |
| ▸ | CA1 | P00915 | 5/20 | 0.69 |
| ▸ | CA2 | P00918 | 5/20 | 0.69 |
| ▸ | CA7 | P43166 | 5/20 | 0.69 |
| ▸ | CA9 | Q16790 | 5/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.69 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.54 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122473 | 1.00 | CA12 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23045197 | 0.98 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL135979 | 0.84 | CA12 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27361124 | 0.84 | CSNK2A1 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1206018 | 0.83 | CYP46A1 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27628979 | 0.82 | CSNK2A1 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23045195 | 0.82 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10819683 | 0.82 | CSNK2A1 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1170022 | 0.82 | CYP46A1 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30364839 | 0.82 | CYP46A1 (0.56) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611741-A1 | TARGETING ALLOSTERIC AND ORTHOSTERIC POCKETS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097721-A1 | TARGETING ALLOSTERIC AND ORTHOSTERIC POCKETS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2024-05-10 | — | — | WO | disclosed |
| EP-4333984-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022235574-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-4007748-A1 | ENOL ETHER PROPERFUME | Firmenich SA (CH) | 2022-06-08 | — | — | EP | disclosed |