SCHEMBL135979

SCHEMBL135979

COC(=O)c1ccc(C)cc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.69
CA1 P00915 3/20 0.69
CA2 P00918 3/20 0.69
CA7 P43166 3/20 0.69
CA9 Q16790 3/20 0.69
CA14 Q9ULX7 3/20 0.69
PDK2 Q15119 1/20 0.69
PDK4 Q16654 1/20 0.69
GAA P10253 2/20 0.65
MYC P01106 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.59
LMNA P02545 1/20 0.57
TSHR P16473 1/20 0.57
IDO1 P14902 1/20 0.55
TDO2 P48775 1/20 0.55
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
NR4A2 P43354 2/20 0.51
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23045195 0.98 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL23231570 0.85 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL122473 0.84 CA12 (0.69) CA12CA1CA2CA7CA9
SCHEMBL27257996 0.84 IDO1 (0.51) CA12CA1CA2CA7CA9
SCHEMBL29640522 0.84 CA12 (0.69) CA12CA1CA2CA7CA9
SCHEMBL1206018 0.83 CYP46A1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL27341785 0.82 NPC1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL23045197 0.82 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL28138691 0.82 NPC1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL27460303 0.82 NPC1 (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240886-A Method for synthesizing ethyl salicylate compound by biological enzyme catalysis 济南大学 2024-06-25 CN claimed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
CN-103694738-B Isothiazole class dye composite and the method for dacron fabric short route basic dyeing thereof SUZHOU UNIVERSITY (CN) 2016-01-20 CN claimed
CN-105218329-A Clean analogue intermediate of a kind of row and preparation method thereof SHANGHAI INST TECHNOLOGY 2016-01-06 CN claimed
CN-103694738-A Isothiazole dye composition and method for applying isothiazole dye composition into short-process alkaline dyeing of polyester fabric UNIV SOOCHOW 2014-04-02 CN claimed
CN-103044963-A Dye composition and method for short-process alkaline dyeing of polyester fiber fabric by using same UNIV SOOCHOW 2013-04-17 CN claimed
US-6458757-B1 PROCESS FOR THE PRODUCTION OF PERFUMING COMPOSITIONS, PERFUMED PRODUCTS AND SUBSTANCES FOR PERFUMERY CHARACTERIZED IN THAT THEY COMPRISE, AS AN ACTIVE INGREDIENT WITH AN INFLUENCE ON THE SCENT, AN EFFECTIVE QUANTITY OF AN ALKYLSALICYLIC ACID Chimie, Rhodia (FR) 2002-10-01 US claimed
EP-0876325-B1 METHOD FOR PREPARING SCENTING COMPOSITIONS AND SCENTED PRODUCTS, AND RESULTING PRODUCTS RHODIA CHIMIE SA (FR) 2002-01-09 EP claimed
US-20260138969-A1 TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-05-21 US disclosed
CN-122037370-A Conductive polypropylene composition, and preparation method and application thereof 中国石油化工股份有限公司 2026-05-15 CN disclosed
US-12590062-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
US-20250377364-A1 REAGENT, METHOD, AND DEVICE FOR DETECTING ALBUMIN NEC CORPORATION (JP) 2025-12-11 US disclosed
US-20250320318-A1 OLEFIN POLYMERIZATION CATALYST COMPONENT, CATALYST SYSTEM, PREPOLYMERIZATION CATALYST COMPOSITION AND OLEFIN POLYMERIZATION METHOD CHINA PETROLEUM & CHEM CORP (CN) 2025-10-16 US disclosed
EP-3745105-B1 TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME HITACHI LTD (JP) 2025-08-27 EP disclosed
EP-0348155-A1 Quinoline derivatives as antagonists of leukotriene D4, compositions containing the same and processes for their preparation RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1989-12-27 EP disclosed
CN-87100978-A Dihydrobenzofuran-and chroman-carboxamide derivatives, processes for their preparation and their use as neuroleptics 1987-09-16 CN disclosed
CN-85109587-A Have the new benzothiophene kind of antiallergic activity and the preparation method of benzofuran compounds 1986-12-17 CN disclosed
EP-0083228-B1 PHARMACEUTICALLY ACTIVE PHENYLCARBOXYLIC ACID DERIVATIVES ICI AMERICAS INC. (US) 1985-05-15 EP disclosed
US-4499299-A Pharmaceutically active phenylcarboxylic acid derivatives ICI AMERICAS INC. (US) 1985-02-12 US disclosed
EP-0083228-A1 Pharmaceutically active phenylcarboxylic acid derivatives ICI AMERICAS INC. (US) 1983-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138969-A1 TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF CASP1, CASP3, BAD CA12 4257/4885CA1 278/4885CA2 2530/4885
US-20250377364-A1 REAGENT, METHOD, AND DEVICE FOR DETECTING ALBUMIN ALB, TTR, MTTP CA12 367/4885CA1 1488/4885CA2 3341/4885
US-12590062-B2 PD-1/PD-L1 inhibitors CD274, PDCD1LG2, PDCD1 CA12 2207/4885CA1 2733/4885CA2 3359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.