Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13401629 | 0.81 | ALDH1A1 (0.49) | RXFP1KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29640525 | 0.80 | KDM4E (0.47) | RXFP1KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29640450 | 0.78 | RXFP1 (0.73) | RXFP1KDM4EPOLBKMT2A | |
| SCHEMBL29712166 | 0.76 | RXFP1 (0.51) | RXFP1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1775497 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL24155930 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL7227594 | 0.74 | HPGD (0.47) | RXFP1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31735817 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL4797576 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL2695540 | 0.71 | KDM4E (0.47) | RXFP1KDM4EALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450006-A | TrkB positive allosteric modulators | 斯特拉斯堡大学 | 2022-05-06 | — | — | CN | disclosed |