Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13401629 | 0.87 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2METKMT2A | |
| SCHEMBL29640527 | 0.80 | RXFP1 (0.46) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL2420906 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2METKMT2A | |
| SCHEMBL24770720 | 0.74 | RXFP1 (0.62) | KDM4EKMT2APOLBRXFP1 | |
| SCHEMBL2695540 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2METKMT2A | |
| SCHEMBL3711939 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2METKMT2A | |
| SCHEMBL4797576 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2METKMT2A | |
| SCHEMBL31735817 | 0.73 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2METKMT2A | |
| SCHEMBL23116158 | 0.70 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2METKMT2A | |
| SCHEMBL28741968 | 0.70 | SIGMAR1 (0.56) | KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450006-A | TrkB positive allosteric modulators | 斯特拉斯堡大学 | 2022-05-06 | — | — | CN | disclosed |