Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601136 | 1.00 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL24584847 | 1.00 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL30601089 | 1.00 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL24585120 | 1.00 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL30601115 | 1.00 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL24584846 | 1.00 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL29085378 | 0.86 | CCNA2 (0.46) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL29085379 | 0.86 | CCNA2 (0.46) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL24585103 | 0.86 | LMNA (0.46) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL30601127 | 0.86 | LMNA (0.46) | CCNA2CDK2CCNA1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140425-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS IRAK4 INHIBITORS AND THEIR USE IN THE TREATMENT OF DISEASE | BIOGEN MA INC. (US) | 2022-06-30 | — | — | WO | disclosed |