Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 4/20 | 0.41 |
| ▸ | GABRD | O14764 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.41 |
| ▸ | GABRE | P78334 | 4/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29085379 | 1.00 | CCNA2 (0.46) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL30601115 | 0.86 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL30601136 | 0.86 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL30601089 | 0.86 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL24584847 | 0.86 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL24585120 | 0.86 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL29640644 | 0.86 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL24584846 | 0.86 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL22835056 | 0.85 | P2RX3 (0.42) | CCNA2CDK2CCNA1CDK1CCNB1 | |
| SCHEMBL22843030 | 0.77 | NUDT1 (0.53) | CCNA2CDK2CCNA1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867781-A | Imidazo [1,2-a ] pyridine derivatives as IRAK4 inhibitors and their use in the treatment of diseases | 渤健马萨诸塞州股份有限公司 | 2023-10-10 | — | — | CN | disclosed |