Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23362293 | 1.00 | KDM1A (0.43) | KDM1AKDM1BKCNH2BACE1AKR1B1 | |
| SCHEMBL29640596 | 0.79 | HTR2C (0.40) | — | |
| SCHEMBL23362302 | 0.79 | HTR2C (0.40) | — | |
| SCHEMBL28768381 | 0.76 | SLC9A1 (0.36) | KDM1AKDM1BKCNH2BACE1AKR1B1 | |
| SCHEMBL23362524 | 0.75 | KDM1A (0.36) | KDM1AKDM1B | |
| SCHEMBL29640629 | 0.75 | KDM1A (0.36) | KDM1AKDM1B | |
| SCHEMBL23363127 | 0.74 | AKR1B1 (0.38) | KDM1AKDM1BKCNH2AKR1B1 | |
| SCHEMBL20449182 | 0.70 | KDM1A (0.45) | KDM1AKDM1BKCNH2 | |
| SCHEMBL23362436 | 0.68 | AKR1B1 (0.36) | KDM1AKDM1BBACE1AKR1B1 | |
| SCHEMBL29640614 | 0.68 | AKR1B1 (0.36) | KDM1AKDM1BBACE1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641477-A | Novel compound having inhibitory activity against glucose ceramide synthase or pharmaceutically acceptable salt thereof, method for preparing same, and pharmaceutical composition comprising same | 柳韩洋行 | 2022-06-17 | — | — | CN | disclosed |