SCHEMBL29640709

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	7/20	0.54

▸	NPY4R	P50391	7/20	0.54

▸	NPY5R	Q15761	7/20	0.54

▸	NPY1R	P25929	7/20	0.54

▸	CXCL8	P10145	5/20	0.54

▸	CALCR	P30988	3/20	0.54

▸	F2	P00734	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29930217	0.92	CXCL8 (0.56)	CXCL8CALCR
SCHEMBL31258335	0.89	CXCL8 (0.53)	CXCL8CALCR
SCHEMBL29814922	0.84	NPY2R (0.61)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31182806	0.83	CALCR (0.65)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30658198	0.82	CALCR (0.70)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29797079	0.81	OPRD1 (0.53)	CXCL8
SCHEMBL31182922	0.81	CALCR (0.71)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL17722479	0.80	CXCL8 (0.62)	NPY2RNPY4RNPY5RNPY1RCXCL8
SCHEMBL38660346	0.80	OPRD1 (0.62)	NPY2RNPY4RNPY5RNPY1RF2
SCHEMBL31332000	0.80	NMUR2 (0.61)	NPY2RNPY4RNPY5RNPY1RCXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114450294-A	Polypeptide with MMP2 inhibitory effect	大正制药株式会社	2022-05-06	—	—	CN	disclosed