Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035634 | 0.81 | ALDH1A1 (0.51) | ALDH1A1AKR1C3HPGDHRH3HRH1 | |
| SCHEMBL1269266 | 0.81 | ALDH1A1 (0.51) | ALDH1A1AKR1C3HPGDHRH3HRH1 | |
| SCHEMBL1727049 | 0.80 | AKR1C3 (0.52) | ALDH1A1AKR1C3HPGDHRH3KMT2A | |
| SCHEMBL30088471 | 0.80 | ALDH1A1 (0.50) | ALDH1A1AKR1C3HPGDHRH3HRH1 | |
| SCHEMBL30731050 | 0.80 | ALDH1A1 (0.50) | ALDH1A1AKR1C3HPGDHRH3HRH1 | |
| SCHEMBL23832364 | 0.80 | ALDH1A1 (0.50) | ALDH1A1AKR1C3HPGDHRH3HRH1 | |
| SCHEMBL3605010 | 0.80 | ALDH1A1 (0.50) | ALDH1A1AKR1C3HPGDHRH3HRH1 | |
| SCHEMBL25184171 | 0.79 | KMT2A (0.50) | ALDH1A1AKR1C3MEN1KMT2ALMNA | |
| SCHEMBL11142367 | 0.78 | ALDH1A1 (0.74) | ALDH1A1AKR1C3HPGDTSHRCYP1A2 | |
| SCHEMBL13456031 | 0.78 | ALDH1A1 (0.47) | ALDH1A1AKR1C3HPGDHRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | PFIZER INC. (US) | 2025-10-16 | — | — | US | disclosed |
| WO-2025215579-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS | PFIZER INC. (US) | 2025-10-16 | — | — | WO | disclosed |
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | HRH4, HNMT, NNT | ALDH1A1 2633/4885AKR1C3 553/4885HPGD 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.