Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 6/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.35 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21275403 | 1.00 | MKNK1 (0.37) | MKNK1MKNK2PIK3CAMAP3K14ALOX5AP | |
| SCHEMBL24103874 | 0.85 | ENPP3 (0.41) | MAP3K14LMNAMAPTTHRBGPR119 | |
| SCHEMBL15885628 | 0.79 | HPGD (0.33) | PIK3CAMAP3K14ABL1 | |
| SCHEMBL3075849 | 0.77 | GPR119 (0.43) | PTK2GPR119 | |
| SCHEMBL24103053 | 0.76 | MAPT (0.47) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL24122320 | 0.75 | PTPN2 (0.36) | MAP3K14ALDH1A1LMNAMAPTTHRB | |
| SCHEMBL6896660 | 0.72 | KIT (0.52) | PIK3CAMAPTGPR119 | |
| SCHEMBL1852996 | 0.72 | KLK3 (0.44) | PIK3CAALDH1A1GAALMNAMAPT | |
| SCHEMBL13312280 | 0.72 | MAPT (0.42) | KDM4EALDH1A1LMNAMAPTTHRB | |
| SCHEMBL12137933 | 0.71 | CKS1B (0.46) | PIK3CAMAPTGPR119RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |