SCHEMBL2964129

SCHEMBL2964129

CC1=Cc2c(Br)ccc(-c3ccccc3)c2C1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.40
IL1RN P18510 1/20 0.40
ERAP2 Q6P179 1/20 0.40
ERAP1 Q9NZ08 1/20 0.40
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
PARP10 Q53GL7 1/20 0.33
PARP11 Q9NR21 1/20 0.33
ESR2 Q92731 1/20 0.33
PRCP P42785 1/20 0.32
LMNA P02545 1/20 0.31
CYP2A6 P11509 2/20 0.31
CYP2B6 P20813 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2975616 0.87 ANPEP (0.40) ANPEPIL1RNERAP2ERAP1ALDH1A1
SCHEMBL2974367 0.87 NPC1 (0.30) ALDH1A1
SCHEMBL2974370 0.82 ALDH1A1 (0.35) ALDH1A1
SCHEMBL690132 0.78
SCHEMBL2974698 0.77 ANPEP (0.36) ANPEPIL1RNERAP2ERAP1ALDH1A1
SCHEMBL2963885 0.77 ALDH1A1 (0.37) ALDH1A1LMNACYP2A6MAOB
SCHEMBL2970572 0.77 RARB (0.36) ALDH1A1MAPK1
SCHEMBL2974526 0.76 MAOA (0.31) MAOB
SCHEMBL2972165 0.75 ALDH1A1 (0.35) ANPEPIL1RNERAP2ERAP1ALDH1A1
SCHEMBL2976302 0.74 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 ANPEP 4113/4885IL1RN 3140/4885ERAP2 4372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.