Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20232640 | 1.00 | BRD4 (0.52) | BRD4BCHEMAPTMEN1GAA | |
| SCHEMBL22598871 | 0.88 | BRD4 (0.51) | BRD4BCHEMEN1GAAKMT2A | |
| SCHEMBL29642355 | 0.88 | BRD4 (0.51) | BRD4BCHEMAPTMEN1GAA | |
| SCHEMBL20232553 | 0.88 | BRD4 (0.51) | BRD4BCHEMAPTMEN1GAA | |
| SCHEMBL20232495 | 0.88 | BRD4 (0.51) | BRD4BCHEMEN1GAAKMT2A | |
| SCHEMBL29642253 | 0.85 | BRD4 (0.56) | BRD4ALDH1A1 | |
| SCHEMBL20232496 | 0.85 | BRD4 (0.56) | BRD4ALDH1A1 | |
| SCHEMBL20232558 | 0.83 | BRD4 (0.56) | BRD4MEN1GAAKMT2A | |
| SCHEMBL29642323 | 0.83 | BRD4 (0.56) | BRD4MEN1GAAKMT2A | |
| SCHEMBL20232561 | 0.82 | BRD4 (0.46) | BRD4MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089549-A1 | INHIBITORS OF PROTEIN ARGININE DEIMINASES (PADS) AND METHODS OF PREPARATION AND USE THEREOF | UNIV MASSACHUSETTS (US) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089549-A1 | INHIBITORS OF PROTEIN ARGININE DEIMINASES (PADS) AND METHODS OF PREPARATION AND USE THEREOF | PADI2, PADI1, PADI4 | BRD4 1424/4885BCHE 333/4885MAPT 3793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.