PADI2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL10060140	0.53	10/20
SCHEMBL10061245	0.48	9/20
SCHEMBL8587073	0.57	6/20
SCHEMBL4650854	0.46	6/20
SCHEMBL2699874	0.74	5/20
SCHEMBL2699878	0.74	5/20
SCHEMBL10026327	0.72	5/20
SCHEMBL1979621	0.66	5/20
SCHEMBL8639063	0.65	5/20
SCHEMBL1979577	0.63	5/20
SCHEMBL1979695	0.62	5/20
SCHEMBL10060566	0.51	5/20
SCHEMBL7751919	0.50	5/20
SCHEMBL10060141	0.50	5/20
SCHEMBL8111786	0.49	5/20
SCHEMBL10060144	0.48	5/20
SCHEMBL8114285	0.48	5/20
SCHEMBL9286645	0.48	5/20
SCHEMBL1388417	0.43	5/20
SCHEMBL4729919	1.00	4/20

Clinical trials — most relevant to PADI2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
L-Arginine Role for Stone Lower Ureter : A Randomized Control Study	PHASE4	COMPLETED
L-arginine Treatment in Mild Hypertension	PHASE4	UNKNOWN
Vascular Function Intervention Trial in Sickle Cell Disease	PHASE2/PHASE3	UNKNOWN
Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial	PHASE3	COMPLETED
L-Arginine in Pre-Eclampsia	PHASE3	COMPLETED
Effect of Rosiglitazone on ADMA in Critical Illness	PHASE3	UNKNOWN
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis	PHASE2	RECRUITING
Intravenous L-Citrulline Influence on the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19	PHASE2	COMPLETED
Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients	PHASE2	COMPLETED
STRETCH Study: Effect of Distensibility on Endothelial-Dependent Vasoreactivity in Patients With ISH	PHASE2	COMPLETED
The Effects of NOx and Conjugated Linoleic Acid on Asthmatics	PHASE2	COMPLETED
ADI-PEG20, Obesity and Prediabetes	PHASE2	WITHDRAWN
iNOS With Positron Emission Tomography (PET) in Cellular Inflammation.	EARLY_PHASE1	COMPLETED
Study of the Articular Microbiota in Rheumatoid Arthritis.	nan	COMPLETED
Effect of Nonsurgical Periodontal Therapy (NSPT) on Rheumatoid Arthritis Subjects With Periodontitis	nan	COMPLETED
Serum Anti-PCOLCE as Novel Diagnostic Biomarker in Rheumatoid Arthritis With Emphasis on Seronegative Patients.	nan	NOT_YET_RECRUITING
Clinical Trial for Evaluation of Vermillion's Blood Test to Predict the Probability of Peripheral Artery Disease	nan	COMPLETED
Effects of Trehalose and Polyphenols in Vasculopathic Patients	nan	COMPLETED
Impact of Antiglycemic & Immunosuppressive Therapies on NETosis in Diabetes & Kidney Disease (NETs - Neutrophil Traps)	nan	RECRUITING
Effect Assessment of Periodontal Prophylaxis on Rheumatoid Arthritis Activity.	nan	COMPLETED
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD	nan	COMPLETED
Effect of Arginine and Glutamine on Radiation-induced Oral Mucositis: a Trible Blinded Randomized Controlled Clinical Trial	nan	COMPLETED
Study of Arginine and Nitric Oxide in Patients With Diabetes	nan	COMPLETED
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients	nan	COMPLETED
L-Arginine, Symmetrical and Asymmetrical Dimethylarginine (SDMA/ADMA) in Acute Kidney Injury (AKI)	nan	COMPLETED
Study on PAD and CAS Based on Omics and Imaging	nan	NOT_YET_RECRUITING
The Clinical Value of the Nitric Oxide System Components in Asthma and COPD	nan	UNKNOWN
Arginine Synthesis in Healthy Adult Humans	nan	COMPLETED
Effectiveness of Combined Aerobic and Strength Training in Acute and Chronic Adaptations in Patients With Heart Failure	nan	COMPLETED
Preterm Arginine INTake Study	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PADI2 binder may also engage these)

Protein	Name	Similarity
P20717	—	1.000	P20717 →
Q08642	—	1.000	Q08642 →
PADI1	Protein-arginine deiminase type-1	1.000	landscape →
O88807	—	1.000	O88807 →
PADI4	Protein-arginine deiminase type-4	1.000	landscape →
Q8K3V4	—	1.000	Q8K3V4 →
Q9Z185	—	1.000	Q9Z185 →
PADI3	Protein-arginine deiminase type-3	0.999	landscape →
O02849	—	0.999	O02849 →
Q9Z183	—	0.998	Q9Z183 →
PADI6	Inactive protein-arginine deiminase type-6	0.997	landscape →
P70708	—	0.997	P70708 →
Q9Z184	—	0.995	Q9Z184 →
O88806	—	0.992	O88806 →
AS3MT	Arsenite methyltransferase	0.991	landscape →
Q8VHT6	—	0.990	Q8VHT6 →
Q2QEI3	—	0.988	Q2QEI3 →
Q92562	—	0.988	Q92562 →
Q8BJM7	—	0.988	Q8BJM7 →
Q95JR7	—	0.988	Q95JR7 →
Q7TNB8	—	0.988	Q7TNB8 →
KDM5D	Lysine-specific demethylase 5D	0.987	landscape →
Q8WUF8	—	0.987	Q8WUF8 →
Q6W3E5	—	0.986	Q6W3E5 →
Q5ZK44	—	0.986	Q5ZK44 →
Q5XUN4	—	0.986	Q5XUN4 →
Q99M64	—	0.986	Q99M64 →
Q0VA04	—	0.986	Q0VA04 →
Q9Z8R3	—	0.986	Q9Z8R3 →
Q6RJS2	—	0.986	Q6RJS2 →