Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.68 |
| ▸ | CA1 | P00915 | 5/20 | 0.68 |
| ▸ | CA9 | Q16790 | 5/20 | 0.68 |
| ▸ | CA6 | P23280 | 3/20 | 0.68 |
| ▸ | CA12 | O43570 | 3/20 | 0.68 |
| ▸ | CA4 | P22748 | 2/20 | 0.68 |
| ▸ | CA5A | P35218 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.46 |
| ▸ | FEN1 | P39748 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1080972 | 0.89 | CA2 (0.61) | CA2CA1CA9CA6CA12 | |
| SCHEMBL8347239 | 0.86 | CA2 (0.58) | CA2CA1CA9CA6CA12 | |
| SCHEMBL4923246 | 0.84 | GAA (0.67) | CA2CA1CA9CA6CA12 | |
| SCHEMBL672207 | 0.83 | CA1 (0.52) | CA2CA1CA9CA6CA12 | |
| SCHEMBL30074528 | 0.81 | CA2 (1.00) | CA2CA1CA9CA6CA12 | |
| SCHEMBL183126 | 0.81 | CA2 (1.00) | CA2CA1CA9CA6CA12 | |
| Methane SCHEMBL18230300 | 0.79 | CA2 (0.95) | CA2CA1CA9CA6CA12 | |
| SCHEMBL7967712 | 0.78 | CA2 (0.50) | CA2CA1CA9CA6CA12 | |
| SCHEMBL28882144 | 0.78 | STAT3 (0.56) | CA2CA1CA9CA6CA12 | |
| SCHEMBL6820364 | 0.78 | CA2 (0.50) | CA2CA1CA9CA6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7770534-B2 | Changed condition indicator | THERMOPROX | 2010-08-10 | — | — | US | disclosed |
| EP-1994385-A2 | CHANGED CONDITION INDICATOR | Cooperman, Isadore (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007106463-A2 | CHANGED CONDITION INDICATOR | COOPERMAN ISADORE (US) | 2007-09-20 | — | — | WO | disclosed |
| US-20070151502-A1 | Changed condition indicator | THERMOPROX | 2007-07-05 | — | — | US | disclosed |
| EP-1377543-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083630-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |
| EP-0598843-B1 | ARAMID PARTICLES AS WEAR ADDITIVES | DU PONT (US) | 1996-03-20 | — | — | EP | disclosed |
| EP-0598843-A1 | ARAMID PARTICLES AS WEAR ADDITIVES. | DU PONT (US) | 1994-06-01 | — | — | EP | disclosed |
| WO-1993004300-A1 | ARAMID PARTICLES AS WEAR ADDITIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |