Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 9/20 | 0.50 |
| ▸ | CA1 | P00915 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.45 |
| ▸ | FEN1 | P39748 | 3/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1080972 | 0.89 | CA2 (0.61) | CA2CA9CA1CA12CA6 | |
| SCHEMBL3823918 | 0.87 | LRRK2 (0.44) | CA2CA9CA1CA12CA6 | |
| SCHEMBL8347239 | 0.86 | CA2 (0.58) | CA2CA9CA1CA12CA6 | |
| SCHEMBL391939 | 0.84 | CA2 (0.56) | CA2CA9CA1CA12CA6 | |
| Hydrochloric Acid SCHEMBL6754825 | 0.82 | CA2 (0.54) | CA2CA9CA1CA12CA6 | |
| Hydrochloric Acid SCHEMBL5740459 | 0.82 | CA2 (0.54) | CA2CA9CA1CA12CA6 | |
| SCHEMBL3823915 | 0.81 | STAT3 (0.47) | CA2CA9CA1CA12CA6 | |
| SCHEMBL1116406 | 0.81 | CA2 (0.56) | CA2CA9CA1CA12CA6 | |
| Ammonia Solution, Strong SCHEMBL28645552 | 0.79 | CA2 (0.55) | CA2CA9CA1CA12CA6 | |
| SCHEMBL17922579 | 0.78 | HSD11B1 (0.47) | CA2CA9CA1CA12ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |