Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 10/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643225 | 0.85 | RORC (0.56) | RORCALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29643269 | 0.85 | RORC (0.56) | RORCALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29629312 | 0.81 | HPGD (0.65) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29629313 | 0.81 | HPGD (0.65) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8922345 | 0.81 | HPGD (0.65) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2734561 | 0.80 | ALDH1A1 (0.78) | HPGDALDH1A1MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL8920877 | 0.80 | HPGD (0.63) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL16119994 | 0.80 | HPGD (0.54) | RORCHPGDALDH1A1MAPTHTT | |
| Formaldehyde SCHEMBL27586290 | 0.78 | ALDH1A1 (0.74) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL13866623 | 0.77 | PTGER4 (0.59) | RORCHPGDALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |