Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | F2 | P00734 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586929 | 1.00 | MAPT (0.70) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10738593 | 0.98 | MAPT (0.68) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4283723 | 0.97 | MAPT (0.66) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17444700 | 0.91 | MAPT (0.60) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14635243 | 0.90 | HSD17B10 (0.63) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30201480 | 0.88 | MAPT (0.63) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2484751 | 0.88 | MAPT (0.63) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4258762 | 0.86 | MAPT (0.68) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6447738 | 0.86 | F2 (0.74) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29643283 | 0.86 | F2 (0.74) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |