Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | MPL | P40238 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484751 | 1.00 | MAPT (0.63) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL2220908 | 0.90 | ALDH1A1 (0.57) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14651018 | 0.88 | SMN1; SMN2 (0.58) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL29643236 | 0.88 | MAPT (0.70) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL1586929 | 0.88 | MAPT (0.70) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL30571064 | 0.86 | MAPT (0.62) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL10738593 | 0.86 | MAPT (0.68) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4283723 | 0.84 | MAPT (0.66) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL2485234 | 0.82 | MAPT (0.61) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6688391 | 0.81 | MAPT (0.60) | MAPTKMT2AKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |