SCHEMBL29643258

SCHEMBL29643258

COc1ccc2[nH]c3ccccc3c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
KDM4E B2RXH2 3/20 1.00
MAPT P10636 3/20 1.00
HSD17B10 Q99714 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
HPGD P15428 2/20 1.00
TSHR P16473 1/20 0.81
GFER P55789 1/20 0.81
ABCG2 Q9UNQ0 1/20 0.75
CHUK O15111 1/20 0.63
ACHE P22303 3/20 0.61
BCHE P06276 1/20 0.61
ATM Q13315 1/20 0.57
AHR P35869 1/20 0.57
ROCK2 O75116 1/20 0.56
GABRP O00591 1/20 0.56
GABRD O14764 1/20 0.56
GABRA1 P14867 1/20 0.56
GABRB1 P18505 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532262 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL29562964 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL29391519 0.90 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL2597652 0.90 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL13563981 0.90 KDM4E (0.81) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL1181326 0.89 KDM4E (0.79) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL29670412 0.89 KDM4E (0.79) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL30115280 0.89 KDM4E (0.79) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL30213441 0.86 ABCG2 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL21375573 0.86 KDM4E (0.75) ALDH1A1KDM4EMAPTHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717186-B Preparation method and application of clausena lansium alkaloids 江西农业大学 2022-07-12 CN claimed
CN-109206360-B Carbazole amide derivative or salt thereof, and preparation method and application thereof 复旦大学 2022-05-17 CN disclosed