SCHEMBL532262

SCHEMBL532262

COc1ccc2[nH]c3ccccc3c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
KDM4E B2RXH2 3/20 1.00
MAPT P10636 3/20 1.00
HSD17B10 Q99714 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
HPGD P15428 2/20 1.00
TSHR P16473 1/20 0.81
GFER P55789 1/20 0.81
ABCG2 Q9UNQ0 1/20 0.75
CHUK O15111 1/20 0.63
ACHE P22303 3/20 0.61
BCHE P06276 1/20 0.61
ATM Q13315 1/20 0.57
AHR P35869 1/20 0.57
ROCK2 O75116 1/20 0.56
GABRP O00591 1/20 0.56
GABRD O14764 1/20 0.56
GABRA1 P14867 1/20 0.56
GABRB1 P18505 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29643258 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL29562964 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL29391519 0.90 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL2597652 0.90 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL13563981 0.90 KDM4E (0.81) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL1181326 0.89 KDM4E (0.79) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL29670412 0.89 KDM4E (0.79) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL30115280 0.89 KDM4E (0.79) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL30213441 0.86 ABCG2 (1.00) ALDH1A1KDM4EMAPTHSD17B10MEN1
SCHEMBL21375573 0.86 KDM4E (0.75) ALDH1A1KDM4EMAPTHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126050-B 6-Methoxy carbazole alkaloid compound and preparation method and application thereof 云南省肿瘤医院(昆明医科大学第三附属医院) 2024-07-02 CN claimed
CN-118126050-A 6-Methoxy carbazole alkaloid compound and preparation method and application thereof 云南省肿瘤医院(昆明医科大学第三附属医院) 2024-06-04 CN claimed
CN-113372261-B Method for preparing 1-bromo/chloro carbazole and derivatives thereof 中国科学院兰州化学物理研究所 2023-06-27 CN claimed
CN-111072641-B Orange photo-thermal activation delay fluorescent material and synthetic method and application thereof 盐城工学院 2023-05-12 CN claimed
CN-113336694-B Thermally activated sensitized fluorescent dendritic material capable of being processed in solution and preparation method thereof 东南大学 2022-08-26 CN claimed
CN-111606841-B Deep blue photo-thermal crosslinking type thermal activation delayed fluorescence material and preparation method and application thereof 山西穿越光电科技有限责任公司 2022-07-19 CN claimed
CN-113372261-A Method for preparing 1-bromine/chlorocarbazole and derivatives thereof 中国科学院兰州化学物理研究所 2021-09-10 CN claimed
CN-113336694-A Thermally activated sensitized fluorescent dendritic material capable of being processed in solution and preparation method thereof 东南大学 2021-09-03 CN claimed
CN-111606841-A Deep blue photo-thermal crosslinking type thermal activation delayed fluorescence material and preparation method and application thereof 盐城工学院 2020-09-01 CN claimed
CN-111072641-A Orange light thermal activation delayed fluorescence material and synthetic method and application thereof 盐城工学院 2020-04-28 CN claimed
US-4483989-A BENZOYLATION 6-HYDROXYCARBAZOLE, FORMYLATING, CYCLIZATION, AND SAPONIFICATION AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1984-11-20 US claimed
CN-116554087-B Method for synthesizing carbazole compounds by photoinduction 陕西师范大学 2025-05-13 CN disclosed
WO-2024199444-A1 HETEROAROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海翊维康医药有限责任公司 2024-10-03 WO disclosed
CN-113710654-B Polymerizable liquid crystal having carbazole nucleus 罗利克技术有限公司 2024-08-30 CN disclosed
CN-118126050-B 6-Methoxy carbazole alkaloid compound and preparation method and application thereof 云南省肿瘤医院(昆明医科大学第三附属医院) 2024-07-02 CN disclosed
US-4889877-A CARBONLESS COPY PAPER THE STANDARD REGISTER COMPANY (US) 1989-12-26 US disclosed
US-4729792-A DISPERSION, OILS, CURING AGENTS, POLYSALT FORMATION, POLYAMINE, LIPOPHILIC, NONPOLAR THE STANDARD REGISTER COMPANY (US) 1988-03-08 US disclosed
EP-0223428-A1 Process for producing oil-containing microcapsules THE STANDARD REGISTER COMPANY (US) 1987-05-27 EP disclosed
US-4360548-A MICROENCAPSULATION OF AT LEAST ONE REACTANT PAIR THE STANDARD REGISTER COMPANY (US) 1982-11-23 US disclosed
US-4111850-A CHARGE TRANSFER COMPLEX OF A FLUORENONE AND A CARBAZOLE AMP INCORPORATED (US) 1978-09-05 US disclosed