SCHEMBL29643373

SCHEMBL29643373

[Li]C(CC(O[SiH3])(c1ccccc1)c1ccccc1)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1317835 0.78 MAPK1 (0.35) MAPK1TAAR1ALDH1A1ALOX15CYP2C19
SCHEMBL18662228 0.76 HTR2A (0.38) MAPK1TAAR1
SCHEMBL1314755 0.74 GRIN1 (0.37) MAPK1
SCHEMBL1313614 0.74 MAPK1 (0.43) MAPK1TAAR1ALDH1A1ALOX15CYP2C19
SCHEMBL2238102 0.71 KCNN4 (0.40) MAPK1TAAR1ALDH1A1ALOX15
SCHEMBL29546596 0.69 MAPK1 (0.39) MAPK1TAAR1ALDH1A1ALOX15
SCHEMBL3482436 0.68 KCNN4 (0.38) MAPK1TAAR1ALDH1A1ALOX15CYP2C19
SCHEMBL22551444 0.67 MAPK1 (0.34) MAPK1TAAR1ALDH1A1ALOX15CYP2C19
SCHEMBL1262885 0.67 TSHR (0.39) MAPK1TAAR1ALDH1A1ALOX15CYP2C19
SCHEMBL4079192 0.67 MAPK1 (0.34) MAPK1TAAR1ALDH1A1ALOX15CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112625159-B Preparation method and application of catalyst for synthesizing hydroxyl-terminated trans-1, 4-polyisoprene polymer 青岛竣翔科技有限公司 2022-05-10 CN disclosed