SCHEMBL4079192

SCHEMBL4079192

[SiH3]OC(CI)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.34
KCNN4 O15554 4/20 0.33
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
KIF11 P52732 2/20 0.33
ALOX15 P16050 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
CASP1 P29466 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4078047 0.83 ALDH1A1 (0.34) MAPK1KCNN4ALDH1A1TSHRKIF11
SCHEMBL4076790 0.77 MAPK1 (0.34) MAPK1KCNN4ALDH1A1TSHRKIF11
SCHEMBL22551444 0.77 MAPK1 (0.34) MAPK1KCNN4ALDH1A1TSHRKIF11
SCHEMBL2238102 0.77 KCNN4 (0.40) MAPK1KCNN4ALDH1A1KIF11ALOX15
SCHEMBL1262885 0.77 TSHR (0.39) MAPK1KCNN4ALDH1A1TSHRKIF11
SCHEMBL28724138 0.77 LMNA (0.35) MAPK1KCNN4ALDH1A1TSHRKIF11
SCHEMBL1313614 0.76 MAPK1 (0.43) MAPK1KCNN4ALDH1A1ALOX15TAAR1
SCHEMBL238218 0.76 CYP1A2 (0.48) MAPK1TSHRKIF11TAAR1CYP1A2
SCHEMBL18662228 0.74 HTR2A (0.38) MAPK1TAAR1
SCHEMBL3482436 0.74 KCNN4 (0.38) MAPK1KCNN4ALDH1A1TSHRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed