Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643790 | 0.74 | POLB (0.36) | TLR7ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL26489875 | 0.71 | SLC2A1 (0.38) | TLR7KDM4ETDP1SLC2A1ALDH1A1 | |
| SCHEMBL27145046 | 0.70 | RXFP1 (0.36) | KDM4EMAPTRAB9ATDP1RXFP1 | |
| SCHEMBL26109913 | 0.69 | KDM4E (0.40) | TLR7KDM4ERAB9ALMNA | |
| SCHEMBL30971062 | 0.69 | LMNA (0.39) | KDM4EMAPTRXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL26105860 | 0.68 | SLC2A1 (0.37) | TLR7KDM4ESLC2A1 | |
| SCHEMBL31347169 | 0.68 | SLC2A1 (0.37) | TLR7KDM4ESLC2A1 | |
| SCHEMBL26105230 | 0.67 | KDM4E (0.49) | KDM4EMAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL31347186 | 0.67 | KDM4E (0.49) | KDM4EMAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL23809379 | 0.67 | NOTUM (0.38) | KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255904-A2 | NOVEL PAR-2 INHIBITORS | Domain Therapeutics (FR) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117882-A2 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2022-06-09 | — | — | WO | disclosed |