Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347169 | 0.85 | SLC2A1 (0.37) | SLC2A1TLR7KDM4E | |
| SCHEMBL26105860 | 0.85 | SLC2A1 (0.37) | SLC2A1TLR7KDM4E | |
| SCHEMBL29643798 | 0.71 | TLR7 (0.39) | SLC2A1TLR7SMN1; SMN2ALDH1A1P2RX3 | |
| SCHEMBL26105147 | 0.69 | CYP19A1 (0.32) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30611846 | 0.69 | CYP19A1 (0.32) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL21820885 | 0.66 | HDAC1 (0.41) | SLC2A1TLR7 | |
| SCHEMBL15687563 | 0.64 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL30612169 | 0.64 | GLO1 (0.35) | ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL26107263 | 0.64 | GLO1 (0.35) | ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL26108223 | 0.64 | HDAC6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183919-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |